From FastQ data to high confidence variant calls: the Genome Analysis Toolkit best practices pipeline.
Curr Protoc Bioinformatics
; 43: 11.10.1-11.10.33, 2013.
Article
em En
| MEDLINE
| ID: mdl-25431634
ABSTRACT
This unit describes how to use BWA and the Genome Analysis Toolkit (GATK) to map genome sequencing data to a reference and produce high-quality variant calls that can be used in downstream analyses. The complete workflow includes the core NGS data processing steps that are necessary to make the raw data suitable for analysis by the GATK, as well as the key methods involved in variant discovery using the GATK.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Variação Genética
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Software
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Genoma Humano
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article