Restricted expression of viral glycoprotein in vesicular stomatitis virus-infected Drosophila melanogaster cells.
J Gen Virol
; 70 ( Pt 1): 213-8, 1989 Jan.
Article
em En
| MEDLINE
| ID: mdl-2543737
Vesicular stomatitis virus (VSV) establishes a non-cytopathic persistent infection in Drosophila melanogaster cells. The synthesis of the viral glycoprotein G was specifically inhibited during a post-transcriptional step, whereas the synthesis and turnover of its mRNA were not modified compared with the other viral mRNAs. Another viral glycoprotein, migrating slightly faster than G protein on an SDS-polyacrylamide gel, was detected in infected Drosophila cells. This protein showed most of the characteristics of the intracellular Gs protein found in infected vertebrate cells. The amounts of G protein integrated into mature virions and of soluble Gs protein secreted into the culture medium were reduced greatly during VSV infection in Drosophila cells.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Glicoproteínas de Membrana
/
Proteínas do Envelope Viral
/
Regulação da Expressão Gênica
/
Vírus da Estomatite Vesicular Indiana
Limite:
Animals
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article