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Biallelic inactivation of protoporphyrinogen oxidase and hydroxymethylbilane synthase is associated with liver cancer in acute porphyrias.
Schneider-Yin, Xiaoye; van Tuyll van Serooskerken, Anne-Moon; Siegesmund, Marko; Went, Philip; Barman-Aksözen, Jasmin; Bladergroen, Reno S; Komminoth, Paul; Cloots, Roy H E; Winnepenninckx, Véronique J; zur Hausen, Axel; Weber, Markus; Driessen, Ann; Poblete-Gutiérrez, Pamela; Bauer, Peter; Schroeder, Christopher; van Geel, Michel; Minder, Elisabeth I; Frank, Jorge.
Afiliação
  • Schneider-Yin X; Institute of Laboratory Medicine and Swiss Porphyrin Reference Laboratory, Stadtspital Triemli, Zürich, Switzerland.
  • van Tuyll van Serooskerken AM; Department of Dermatology, Maastricht University Medical Center (MUMC), The Netherlands; GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center (MUMC), The Netherlands.
  • Siegesmund M; Department of Dermatology and Skin Cancer Center and European Porphyria Specialist Center, Medical Faculty of the Heinrich Heine University, Düsseldorf, Germany.
  • Went P; Institute of Pathology Enge, Zürich, Switzerland.
  • Barman-Aksözen J; Institute of Laboratory Medicine and Swiss Porphyrin Reference Laboratory, Stadtspital Triemli, Zürich, Switzerland.
  • Bladergroen RS; Department of Dermatology, Maastricht University Medical Center (MUMC), The Netherlands; GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center (MUMC), The Netherlands.
  • Komminoth P; Institute of Pathology, Stadtspital Triemli, Zürich, Switzerland.
  • Cloots RH; Department of Pathology, Maastricht University Medical Center (MUMC), The Netherlands.
  • Winnepenninckx VJ; Department of Pathology, Maastricht University Medical Center (MUMC), The Netherlands.
  • zur Hausen A; Department of Pathology, Maastricht University Medical Center (MUMC), The Netherlands.
  • Weber M; Department of Surgery, Stadtspital Triemli, Zürich, Switzerland.
  • Driessen A; Department of Pathology, Maastricht University Medical Center (MUMC), The Netherlands.
  • Poblete-Gutiérrez P; Department of Dermatology, Annadal Medical Center Maastricht, The Netherlands; Department of Dermatology, Ziekenhuis Oost-Limburg (ZOL) Genk, Belgium.
  • Bauer P; Department of Medical Genetics, University of Tübingen, Tübingen, Germany.
  • Schroeder C; Department of Medical Genetics, University of Tübingen, Tübingen, Germany.
  • van Geel M; Department of Dermatology, Maastricht University Medical Center (MUMC), The Netherlands; GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center (MUMC), The Netherlands.
  • Minder EI; Institute of Laboratory Medicine and Swiss Porphyrin Reference Laboratory, Stadtspital Triemli, Zürich, Switzerland.
  • Frank J; Department of Dermatology, Maastricht University Medical Center (MUMC), The Netherlands; GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center (MUMC), The Netherlands; Department of Dermatology and Skin Cancer Center and European Porphyria Specialist Center, Medi
J Hepatol ; 62(3): 734-8, 2015 Mar.
Article em En | MEDLINE | ID: mdl-25445397
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hidroximetilbilano Sintase / Porfiria Aguda Intermitente / Carcinoma Hepatocelular / Proteínas Mitocondriais / Porfiria Variegada / Protoporfirinogênio Oxidase / Flavoproteínas / Neoplasias Hepáticas / Mutação Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hidroximetilbilano Sintase / Porfiria Aguda Intermitente / Carcinoma Hepatocelular / Proteínas Mitocondriais / Porfiria Variegada / Protoporfirinogênio Oxidase / Flavoproteínas / Neoplasias Hepáticas / Mutação Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article