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Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis.
Melo, Sonia A; Sugimoto, Hikaru; O'Connell, Joyce T; Kato, Noritoshi; Villanueva, Alberto; Vidal, August; Qiu, Le; Vitkin, Edward; Perelman, Lev T; Melo, Carlos A; Lucci, Anthony; Ivan, Cristina; Calin, George A; Kalluri, Raghu.
Afiliação
  • Melo SA; Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA; Division of Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
  • Sugimoto H; Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA; Division of Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
  • O'Connell JT; Division of Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
  • Kato N; Division of Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
  • Villanueva A; Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona 08908, Spain.
  • Vidal A; Department of Pathology, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona 08908, Spain.
  • Qiu L; Department of Obstetrics, Gynecology, and Reproductive Biology, and Department of Medicine, Center for Advanced Biomedical Imaging and Photonics, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
  • Vitkin E; Department of Obstetrics, Gynecology, and Reproductive Biology, and Department of Medicine, Center for Advanced Biomedical Imaging and Photonics, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
  • Perelman LT; Department of Obstetrics, Gynecology, and Reproductive Biology, and Department of Medicine, Center for Advanced Biomedical Imaging and Photonics, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
  • Melo CA; Division of Gene Regulation, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands; Doctoral Programme in Biomedicine and Experimental Biology, Centre for Neuroscience and Cell Biology, 3004-517 Coimbra, Portugal.
  • Lucci A; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Ivan C; Center for RNA Interference and Non-coding RNAs, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
  • Calin GA; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
  • Kalluri R; Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA; Division of Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA. Electronic address: rkalluri@md
Cancer Cell ; 26(5): 707-21, 2014 Nov 10.
Article em En | MEDLINE | ID: mdl-25446899
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / MicroRNAs / Exossomos / Carcinogênese Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / MicroRNAs / Exossomos / Carcinogênese Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article