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Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence.
Payne, Rebecca; Muenchhoff, Maximilian; Mann, Jaclyn; Roberts, Hannah E; Matthews, Philippa; Adland, Emily; Hempenstall, Allison; Huang, Kuan-Hsiang; Brockman, Mark; Brumme, Zabrina; Sinclair, Marc; Miura, Toshiyuki; Frater, John; Essex, Myron; Shapiro, Roger; Walker, Bruce D; Ndung'u, Thumbi; McLean, Angela R; Carlson, Jonathan M; Goulder, Philip J R.
Afiliação
  • Payne R; Department of Paediatrics, University of Oxford, Oxford OX1 3SY, United Kingdom;
  • Muenchhoff M; Department of Paediatrics, University of Oxford, Oxford OX1 3SY, United Kingdom;
  • Mann J; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban 4013, South Africa;
  • Roberts HE; The Institute for Emerging Infections, The Oxford Martin School, University of Oxford, Oxford OX1 3BD, United Kingdom; Nuffield Department of Medicine, University of Oxford, Oxford OX1 3SY, United Kingdom;
  • Matthews P; Department of Paediatrics, University of Oxford, Oxford OX1 3SY, United Kingdom;
  • Adland E; Department of Paediatrics, University of Oxford, Oxford OX1 3SY, United Kingdom;
  • Hempenstall A; Department of Paediatrics, University of Oxford, Oxford OX1 3SY, United Kingdom;
  • Huang KH; The Institute for Emerging Infections, The Oxford Martin School, University of Oxford, Oxford OX1 3BD, United Kingdom; Nuffield Department of Medicine, University of Oxford, Oxford OX1 3SY, United Kingdom;
  • Brockman M; Faculty of Health Sciences, Simon Fraser University, Vancouver, BC V5A 1S6, Canada; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC V6Z 1Y6, Canada;
  • Brumme Z; Faculty of Health Sciences, Simon Fraser University, Vancouver, BC V5A 1S6, Canada; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC V6Z 1Y6, Canada;
  • Sinclair M; Department of Paediatrics, University of Oxford, Oxford OX1 3SY, United Kingdom;
  • Miura T; ViiV Healthcare K. K., Shibuya-ku, Tokyo 151-8566, Japan;
  • Frater J; The Institute for Emerging Infections, The Oxford Martin School, University of Oxford, Oxford OX1 3BD, United Kingdom; Nuffield Department of Medicine, University of Oxford, Oxford OX1 3SY, United Kingdom; Oxford National Institute of Health Research, Biomedical Research Centre, Oxford OX1 3SY, Unit
  • Essex M; Botswana Harvard AIDS Institute Partnership, Gaborone BO 320, Botswana; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02215;
  • Shapiro R; Botswana Harvard AIDS Institute Partnership, Gaborone BO 320, Botswana; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02215;
  • Walker BD; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban 4013, South Africa; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, MA 02139;
  • Ndung'u T; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban 4013, South Africa; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, MA 02139;
  • McLean AR; The Institute for Emerging Infections, The Oxford Martin School, University of Oxford, Oxford OX1 3BD, United Kingdom; Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom; and.
  • Carlson JM; Microsoft Research, eScience Group, Los Angeles, CA 90024.
  • Goulder PJ; Department of Paediatrics, University of Oxford, Oxford OX1 3SY, United Kingdom; HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban 4013, South Africa; philip.goulder@paediatrics.ox.ac.uk.
Proc Natl Acad Sci U S A ; 111(50): E5393-400, 2014 Dec 16.
Article em En | MEDLINE | ID: mdl-25453107
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adaptação Biológica / Antígenos HLA-B / Infecções por HIV / HIV / Evolução Molecular Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Humans País como assunto: Africa Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adaptação Biológica / Antígenos HLA-B / Infecções por HIV / HIV / Evolução Molecular Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Humans País como assunto: Africa Idioma: En Ano de publicação: 2014 Tipo de documento: Article