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Design, synthesis, and DNA sequence selectivity of formaldehyde-mediated DNA-adducts of the novel N-(4-aminobutyl) acridine-4-carboxamide.
Ankers, Elizabeth A; Evison, Benny J; Phillips, Don R; Brownlee, Robert T C; Cutts, Suzanne M.
Afiliação
  • Ankers EA; Department of Chemistry, La Trobe Institute for Molecular Sciences, La Trobe University, Bundoora 3086, Australia.
  • Evison BJ; Department of Biochemistry, La Trobe Institute for Molecular Sciences, La Trobe University, Bundoora 3086, Australia; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.
  • Phillips DR; Department of Biochemistry, La Trobe Institute for Molecular Sciences, La Trobe University, Bundoora 3086, Australia.
  • Brownlee RTC; Department of Chemistry, La Trobe Institute for Molecular Sciences, La Trobe University, Bundoora 3086, Australia.
  • Cutts SM; Department of Biochemistry, La Trobe Institute for Molecular Sciences, La Trobe University, Bundoora 3086, Australia. Electronic address: s.cutts@latrobe.edu.au.
Bioorg Med Chem Lett ; 24(24): 5710-5715, 2014 Dec 15.
Article em En | MEDLINE | ID: mdl-25453806
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acridinas / Desenho de Fármacos / Adutos de DNA / Inibidores da Topoisomerase II / Formaldeído Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acridinas / Desenho de Fármacos / Adutos de DNA / Inibidores da Topoisomerase II / Formaldeído Idioma: En Ano de publicação: 2014 Tipo de documento: Article