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Novel indolizine derivatives with unprecedented inhibitory activity on human farnesyltransferase.
Dumea, Carmen; Belei, Dalila; Ghinet, Alina; Dubois, Joëlle; Farce, Amaury; Bîcu, Elena.
Afiliação
  • Dumea C; Department of Organic Chemistry, Faculty of Chemistry, 'Al. I. Cuza' University of Iasi, B-dul Carol I, Nr. 11, Corp A, 700506 Iasi, Romania.
  • Belei D; Department of Organic Chemistry, Faculty of Chemistry, 'Al. I. Cuza' University of Iasi, B-dul Carol I, Nr. 11, Corp A, 700506 Iasi, Romania.
  • Ghinet A; Department of Organic Chemistry, Faculty of Chemistry, 'Al. I. Cuza' University of Iasi, B-dul Carol I, Nr. 11, Corp A, 700506 Iasi, Romania; Univ Lille Nord de France, F-59000 Lille, France; UCLille, EA GRIIOT (4481), Laboratoire de pharmacochimie, Ecole des Hautes Etudes d'Ingénieur (HEI), 13 rue
  • Dubois J; Institut de Chimie des Substances Naturelles, UPR2301 CNRS, Centre de Recherche de Gif, Avenue de la Terrasse, F-91198 Gif-sur-Yvette Cedex, France.
  • Farce A; Univ Lille Nord de France, F-59000 Lille, France; Faculté des Sciences Pharmaceutiques et Biologiques, EA GRIIOT (4481), IFR114, 3 Rue du Pr Laguesse, B.P. 83, F-59006 Lille, France.
  • Bîcu E; Department of Organic Chemistry, Faculty of Chemistry, 'Al. I. Cuza' University of Iasi, B-dul Carol I, Nr. 11, Corp A, 700506 Iasi, Romania. Electronic address: elena@uaic.ro.
Bioorg Med Chem Lett ; 24(24): 5777-5781, 2014 Dec 15.
Article em En | MEDLINE | ID: mdl-25453818
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Farnesiltranstransferase / Indolizinas Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Farnesiltranstransferase / Indolizinas Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article