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LHT7, a chemically modified heparin, inhibits multiple stages of angiogenesis by blocking VEGF, FGF2 and PDGF-B signaling pathways.
Chung, Seung Woo; Bae, Sang Mun; Lee, Myungjin; Al-Hilal, Taslim A; Lee, Chang Kyung; Kim, Jeong Kon; Kim, In-San; Kim, Sang Yoon; Byun, Youngro.
Afiliação
  • Chung SW; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, South Korea.
  • Bae SM; Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Daegu 700-422, South Korea.
  • Lee M; Department of Otolaryngology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul 138-736, South Korea.
  • Al-Hilal TA; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, South Korea.
  • Lee CK; Division of Magnetic Resonance, Korea Basic Science Institute, Cheongwon, Chungbuk 363-883, South Korea; Department of Radiology, Research Institute of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul 138-736, South Korea.
  • Kim JK; Division of Magnetic Resonance, Korea Basic Science Institute, Cheongwon, Chungbuk 363-883, South Korea; Department of Radiology, Research Institute of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul 138-736, South Korea.
  • Kim IS; Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Daegu 700-422, South Korea; Biomedical Research Institute, Korea Institute of Science and Technology, Seoul 136-791, South Korea.
  • Kim SY; Department of Otolaryngology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul 138-736, South Korea; Biomedical Research Institute, Korea Institute of Science and Technology, Seoul 136-791, South Korea.
  • Byun Y; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, South Korea; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergent Science and Technology, Seoul National University, Seoul 151-742, South Korea. Ele
Biomaterials ; 37: 271-8, 2015 Jan.
Article em En | MEDLINE | ID: mdl-25453957
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Taurocólico / Fator 2 de Crescimento de Fibroblastos / Heparina de Baixo Peso Molecular / Inibidores da Angiogênese / Proteínas Proto-Oncogênicas c-sis / Fator A de Crescimento do Endotélio Vascular / Neovascularização Patológica Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Taurocólico / Fator 2 de Crescimento de Fibroblastos / Heparina de Baixo Peso Molecular / Inibidores da Angiogênese / Proteínas Proto-Oncogênicas c-sis / Fator A de Crescimento do Endotélio Vascular / Neovascularização Patológica Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article