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A potent and selective antimicrobial poly(amidoamine) dendrimer conjugate with LED209 targeting QseC receptor to inhibit the virulence genes of gram negative bacteria.
Xue, Xiao-Yan; Mao, Xing-Gang; Li, Zhi; Chen, Zhou; Zhou, Ying; Hou, Zheng; Li, Ming-Kai; Meng, Jing-Ru; Luo, Xiao-Xing.
Afiliação
  • Xue XY; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, China.
  • Mao XG; Department of Neurosurgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, Xi'an, China.
  • Li Z; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, China.
  • Chen Z; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, China.
  • Zhou Y; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, China.
  • Hou Z; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, China.
  • Li MK; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, China.
  • Meng JR; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, China.
  • Luo XX; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, China. Electronic address: xxluo3@fmmu.edu.cn.
Nanomedicine ; 11(2): 329-39, 2015 Feb.
Article em En | MEDLINE | ID: mdl-25461286

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Resistência a Múltiplos Medicamentos / Dendrímeros / Bactérias Gram-Negativas / Infecções Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Resistência a Múltiplos Medicamentos / Dendrímeros / Bactérias Gram-Negativas / Infecções Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article