[Prevention and treatment of intra-uterine synechiae: Review of the literature]. / Prévention et traitement des synéchies endo-utérines : revue de la littérature.
J Gynecol Obstet Biol Reprod (Paris)
; 44(4): 366-79, 2015 Apr.
Article
em Fr
| MEDLINE
| ID: mdl-25479692
ABSTRACT
Intra-uterine adhesions are a major cause of secondary infertility. The prevalence of adhesions is probably underestimated due to the heterogeneity of the symptoms. An exhaustive literature search using search engines MEDLINE, Pubmed, Cochrane library and Web of Science was performed to make a focus on the origins, consequences and methods of prevention of intra-uterine adhesions. Intra-uterine adhesions are likely to occur after any endo-uterine surgery via dysregulated activation of coagulation chain linked to the inflammatory process. Early and late obstetric complications are also recognized as caused by adhesions. The diagnosis is currently performed by hysteroscopy but it remains an invasive procedure even if it can be done with an ambulatory management. Several research approaches inspired by intra-abdominal surgery for the prevention of pelvic adhesions have been developed. However, no current method of prevention has proven its effectiveness in terms of improving spontaneous fertility. The improvement in surgical practices, the design of new intra-uterine medical devices and new research especially in the field of endometrial stem cells can maybe reduce the rate of adhesions end their complications after intra-uterine surgery.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ginatresia
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
Idioma:
Fr
Ano de publicação:
2015
Tipo de documento:
Article