School-located influenza vaccination reduces community risk for influenza and influenza-like illness emergency care visits.
PLoS One
; 9(12): e114479, 2014.
Article
em En
| MEDLINE
| ID: mdl-25489850
ABSTRACT
BACKGROUND:
School-located influenza vaccination (SLIV) programs can substantially enhance the sub-optimal coverage achieved under existing delivery strategies. Randomized SLIV trials have shown these programs reduce laboratory-confirmed influenza among both vaccinated and unvaccinated children. This work explores the effectiveness of a SLIV program in reducing the community risk of influenza and influenza-like illness (ILI) associated emergency care visits.METHODS:
For the 2011/12 and 2012/13 influenza seasons, we estimated age-group specific attack rates (AR) for ILI from routine surveillance and census data. Age-group specific SLIV program effectiveness was estimated as one minus the AR ratio for Alachua County versus two comparison regions the 12 county region surrounding Alachua County, and all non-Alachua counties in Florida.RESULTS:
Vaccination of â¼50% of 5-17 year-olds in Alachua reduced their risk of ILI-associated visits, compared to the rest of Florida, by 79% (95% confidence interval 70, 85) in 2011/12 and 71% (63, 77) in 2012/13. The greatest indirect effectiveness was observed among 0-4 year-olds, reducing AR by 89% (84, 93) in 2011/12 and 84% (79, 88) in 2012/13. Among all non-school age residents, the estimated indirect effectiveness was 60% (54, 65) and 36% (31, 41) for 2011/12 and 2012/13. The overall effectiveness among all age-groups was 65% (61, 70) and 46% (42, 50) for 2011/12 and 2012/13.CONCLUSION:
Wider implementation of SLIV programs can significantly reduce the influenza-associated public health burden in communities.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Instituições Acadêmicas
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Características de Residência
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Vacinação
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Programas de Imunização
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Serviços Médicos de Emergência
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Influenza Humana
Tipo de estudo:
Clinical_trials
/
Etiology_studies
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Risk_factors_studies
Limite:
Adolescent
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Child
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Child, preschool
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Female
/
Humans
/
Male
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article