Cutaneous squamous cell carcinoma with perineural invasion: report on eight cases and review of the literature.
Dermatology
; 230(2): 135-42, 2015.
Article
em En
| MEDLINE
| ID: mdl-25502983
ABSTRACT
BACKGROUND:
Perineural invasion (PNI) in cutaneous squamous cell carcinoma (SCC) is considered to be a negative prognostic factor. A lot of uncertainty remains regarding the classification, diagnosis, treatment and prognosis of SCC with PNI.OBJECTIVE:
To describe typical courses of SCC with PNI and associated findings in order to suggest an optimized diagnostic and therapeutic approach.METHODS:
We present eight cases of SCC with PNI, considering patient and tumor characteristics, histology, treatment and clinical course regarding local recurrence and metastasization.RESULTS:
SCC patients with PNI have a higher rate of local recurrences and greater risk for metastasization than SCC patients without PNI. Age ranged from 68 to 77 years, 6 patients were male and 2 female, with all tumors localized on the head. Three patients had chronic lymphocytic leukemia.CONCLUSION:
Based on the data of this series and the current literature, we make suggestions for better diagnostic and therapeutic management.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Nervos Periféricos
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Neoplasias Cutâneas
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Neoplasias Faciais
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Carcinoma de Células Escamosas
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Recidiva Local de Neoplasia
Tipo de estudo:
Prognostic_studies
Limite:
Aged
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article