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The selective intravenous inhibitor of the MET tyrosine kinase SAR125844 inhibits tumor growth in MET-amplified cancer.
Egile, Coumaran; Kenigsberg, Mireille; Delaisi, Christine; Bégassat, Françoise; Do-Vale, Véronique; Mestadier, Jessica; Bonche, Fabrice; Bénard, Tsiala; Nicolas, Jean-Paul; Valence, Sandrine; Lefranc, Céline; Francesconi, Elisa; Castell, Christelle; Lefebvre, Anne-Marie; Nemecek, Conception; Calvet, Loreley; Goulaouic, Hélène.
Afiliação
  • Egile C; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Kenigsberg M; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Delaisi C; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Bégassat F; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Do-Vale V; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Mestadier J; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Bonche F; Disposition, Safety and Animal Research, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Bénard T; Lead Generation to Candidate Realization, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Nicolas JP; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Valence S; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Lefranc C; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Francesconi E; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Castell C; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Lefebvre AM; Biotherapeutics, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Nemecek C; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Calvet L; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France.
  • Goulaouic H; Sanofi Oncology, Sanofi Research and Development, Vitry-sur-Seine, France. helene.goulaouic@sanofi.com.
Mol Cancer Ther ; 14(2): 384-94, 2015 Feb.
Article em En | MEDLINE | ID: mdl-25504634
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Azóis / Ureia / Amplificação de Genes / Proteínas Proto-Oncogênicas c-met / Inibidores de Proteínas Quinases / Benzotiazóis Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Azóis / Ureia / Amplificação de Genes / Proteínas Proto-Oncogênicas c-met / Inibidores de Proteínas Quinases / Benzotiazóis Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article