The PDZ motif of the &#945;1C subunit is not required for surface trafficking and adrenergic modulation of CaV1.2 channel in the heart.

Yang, Lin; Katchman, Alexander; Weinberg, Richard L; Abrams, Jeffrey; Samad, Tahmina; Wan, Elaine; Pitt, Geoffrey S; Marx, Steven O

The PDZ motif of the α1C subunit is not required for surface trafficking and adrenergic modulation of CaV1.2 channel in the heart.

Yang, Lin; Katchman, Alexander; Weinberg, Richard L; Abrams, Jeffrey; Samad, Tahmina; Wan, Elaine; Pitt, Geoffrey S; Marx, Steven O.

Afiliação

Yang L; From the Division of Cardiology, Departments of Medicine and Pharmacology, College of Physicians and Surgeons, Columbia University, New York, New York 10032 and.
Katchman A; From the Division of Cardiology, Departments of Medicine and Pharmacology, College of Physicians and Surgeons, Columbia University, New York, New York 10032 and.
Weinberg RL; From the Division of Cardiology, Departments of Medicine and Pharmacology, College of Physicians and Surgeons, Columbia University, New York, New York 10032 and.
Abrams J; From the Division of Cardiology, Departments of Medicine and Pharmacology, College of Physicians and Surgeons, Columbia University, New York, New York 10032 and.
Samad T; From the Division of Cardiology, Departments of Medicine and Pharmacology, College of Physicians and Surgeons, Columbia University, New York, New York 10032 and.
Wan E; From the Division of Cardiology, Departments of Medicine and Pharmacology, College of Physicians and Surgeons, Columbia University, New York, New York 10032 and.
Pitt GS; the Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.
Marx SO; From the Division of Cardiology, Departments of Medicine and Pharmacology, College of Physicians and Surgeons, Columbia University, New York, New York 10032 and sm460@columbia.edu.

J Biol Chem ; 290(4): 2166-74, 2015 Jan 23.

Article em En | MEDLINE | ID: mdl-25505241

Assuntos

Canais de Cálcio Tipo L/química; Canais de Cálcio Tipo L/fisiologia; Coração/fisiologia; Miocárdio/metabolismo; Miócitos Cardíacos/metabolismo; Motivos de Aminoácidos; Animais; Bloqueadores dos Canais de Cálcio/química; Colforsina/química; Epitopos/química; Deleção de Genes; Humanos; Ligantes; Camundongos; Camundongos Transgênicos; Neurônios/metabolismo; Nisoldipino/química; Estrutura Terciária de Proteína; Coelhos; Propriedades de Superfície

Palavras-chave

Adrenergic Stimulation; Calcium Channel; Electrophysiology; Heart; PDZ Domain; Transgenic Mice

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canais de Cálcio Tipo L / Miócitos Cardíacos / Coração / Miocárdio Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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