Regulation of herpesvirus reactivation by host microRNAs.
J Virol
; 89(5): 2456-8, 2015 Mar.
Article
em En
| MEDLINE
| ID: mdl-25540363
ABSTRACT
The interplay between latent and lytic modes of infection is central to successful infection of all herpesviruses, yet knowledge of the determinants that govern reactivation of these viruses from latent to lytic infection is limited. Recently, several studies have identified roles for specific cellular microRNAs in inhibiting reactivation of various herpesviruses, thereby promoting latent infections. These studies are discussed in the context of current knowledge on mechanisms of regulation of reactivation of specific herpesviruses.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ativação Viral
/
Regulação Viral da Expressão Gênica
/
MicroRNAs
/
Interações Hospedeiro-Patógeno
/
Herpesviridae
Limite:
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article