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Hematopoietic IKBKE limits the chronicity of inflammasome priming and metaflammation.
Patel, Meghana N; Bernard, William G; Milev, Nikolay B; Cawthorn, William P; Figg, Nichola; Hart, Dan; Prieur, Xavier; Virtue, Sam; Hegyi, Krisztina; Bonnafous, Stephanie; Bailly-Maitre, Beatrice; Chu, Yajing; Griffin, Julian L; Mallat, Ziad; Considine, Robert V; Tran, Albert; Gual, Philippe; Takeuchi, Osamu; Akira, Shizuo; Vidal-Puig, Antonio; Bennett, Martin R; Sethi, Jaswinder K.
Afiliação
  • Patel MN; Department of Clinical Biochemistry and University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom;
  • Bernard WG; Department of Clinical Biochemistry and University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom; Division of Cardiovascular Medicine, Addenbrooke's Centre for Clinical Investigation, Cambridge CB2 2QQ, United Kingdom;
  • Milev NB; Department of Clinical Biochemistry and University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom;
  • Cawthorn WP; Department of Clinical Biochemistry and University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom;
  • Figg N; Division of Cardiovascular Medicine, Addenbrooke's Centre for Clinical Investigation, Cambridge CB2 2QQ, United Kingdom;
  • Hart D; Department of Clinical Biochemistry and University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom;
  • Prieur X; Department of Clinical Biochemistry and University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom;
  • Virtue S; Department of Clinical Biochemistry and University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom;
  • Hegyi K; Department of Clinical Biochemistry and University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom;
  • Bonnafous S; Team 8, Hepatic Complications in Obesity, INSERM, U1065, Nice, F-06204, Cedex 3, France; Digestive Center, Centre Hospitalier Universitaire of Nice, Nice, F-06202, Cedex 3, France; Faculty of Medecine, University of Nice-Sophia-Antipolis, Nice, F-06107, Cedex 2, France;
  • Bailly-Maitre B; Team 8, Hepatic Complications in Obesity, INSERM, U1065, Nice, F-06204, Cedex 3, France; Digestive Center, Centre Hospitalier Universitaire of Nice, Nice, F-06202, Cedex 3, France; Faculty of Medecine, University of Nice-Sophia-Antipolis, Nice, F-06107, Cedex 2, France;
  • Chu Y; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, United Kingdom; MRC Human Nutrition Research Elsie Widdowson Laboratory, Cambridge CB1 9NL, United Kingdom;
  • Griffin JL; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, United Kingdom; MRC Human Nutrition Research Elsie Widdowson Laboratory, Cambridge CB1 9NL, United Kingdom;
  • Mallat Z; Division of Cardiovascular Medicine, Addenbrooke's Centre for Clinical Investigation, Cambridge CB2 2QQ, United Kingdom;
  • Considine RV; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202; and.
  • Tran A; Team 8, Hepatic Complications in Obesity, INSERM, U1065, Nice, F-06204, Cedex 3, France; Digestive Center, Centre Hospitalier Universitaire of Nice, Nice, F-06202, Cedex 3, France; Faculty of Medecine, University of Nice-Sophia-Antipolis, Nice, F-06107, Cedex 2, France;
  • Gual P; Team 8, Hepatic Complications in Obesity, INSERM, U1065, Nice, F-06204, Cedex 3, France; Digestive Center, Centre Hospitalier Universitaire of Nice, Nice, F-06202, Cedex 3, France; Faculty of Medecine, University of Nice-Sophia-Antipolis, Nice, F-06107, Cedex 2, France;
  • Takeuchi O; Department of Host Defense, Research Institute for Microbial Diseases, Osaka University Yamada-oka, Suita, Osaka 565-0871, Japan.
  • Akira S; Department of Host Defense, Research Institute for Microbial Diseases, Osaka University Yamada-oka, Suita, Osaka 565-0871, Japan.
  • Vidal-Puig A; Department of Clinical Biochemistry and University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom;
  • Bennett MR; Division of Cardiovascular Medicine, Addenbrooke's Centre for Clinical Investigation, Cambridge CB2 2QQ, United Kingdom;
  • Sethi JK; Department of Clinical Biochemistry and University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom; j.sethi@oxon.org.
Proc Natl Acad Sci U S A ; 112(2): 506-11, 2015 Jan 13.
Article em En | MEDLINE | ID: mdl-25540417
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinase I-kappa B / Inflamassomos / Inflamação Tipo de estudo: Etiology_studies Limite: Adult / Animals / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinase I-kappa B / Inflamassomos / Inflamação Tipo de estudo: Etiology_studies Limite: Adult / Animals / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article