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An HIV-1 envelope immunogen with W427S mutation in CD4 binding site induced more T follicular helper memory cells and reduced non-specific antibody responses.
Yu, Hao-Tong; Tian, Dan; Wang, Jia-Ye; Guo, Cai-Xia; Li, Yan; Wang, Xin; Li, Di; Zhang, Feng-Min; Zhuang, Min; Ling, Hong.
Afiliação
  • Yu HT; Department of Microbiology, Harbin Medical University, Harbin, China.
  • Tian D; Department of Microbiology, Harbin Medical University, Harbin, China.
  • Wang JY; Department of Microbiology, Harbin Medical University, Harbin, China; Heilongjiang Provincial Key Lab for Infection and Immunity, Key Lab of Etiology of Heilongjiang Province Education Bureau, Harbin, China.
  • Guo CX; Department of Microbiology, Harbin Medical University, Harbin, China.
  • Li Y; Department of Microbiology, Harbin Medical University, Harbin, China; Heilongjiang Provincial Key Lab for Infection and Immunity, Key Lab of Etiology of Heilongjiang Province Education Bureau, Harbin, China.
  • Wang X; Department of Microbiology, Harbin Medical University, Harbin, China.
  • Li D; Department of Microbiology, Harbin Medical University, Harbin, China; Heilongjiang Provincial Key Lab for Infection and Immunity, Key Lab of Etiology of Heilongjiang Province Education Bureau, Harbin, China.
  • Zhang FM; Department of Microbiology, Harbin Medical University, Harbin, China; Heilongjiang Provincial Key Lab for Infection and Immunity, Key Lab of Etiology of Heilongjiang Province Education Bureau, Harbin, China.
  • Zhuang M; Department of Microbiology, Harbin Medical University, Harbin, China; Heilongjiang Provincial Key Lab for Infection and Immunity, Key Lab of Etiology of Heilongjiang Province Education Bureau, Harbin, China.
  • Ling H; Department of Microbiology, Harbin Medical University, Harbin, China; Heilongjiang Provincial Key Lab for Infection and Immunity, Key Lab of Etiology of Heilongjiang Province Education Bureau, Harbin, China; Department of Parasitology, Harbin Medical University, Harbin, China.
PLoS One ; 9(12): e115047, 2014.
Article em En | MEDLINE | ID: mdl-25546013
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / Proteína gp120 do Envelope de HIV / HIV-1 / Linfócitos T Auxiliares-Indutores / Anticorpos Neutralizantes / Mutação Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / Proteína gp120 do Envelope de HIV / HIV-1 / Linfócitos T Auxiliares-Indutores / Anticorpos Neutralizantes / Mutação Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article