Anthelmintic drug discovery: into the future.
J Parasitol
; 101(2): 125-33, 2015 Apr.
Article
em En
| MEDLINE
| ID: mdl-25584662
ABSTRACT
The last half-century has provided all of the (few) drugs currently used to treat human helminthiases. Concern regarding the long-term utility of these drugs, given how readily resistance evolves in the veterinary-agricultural sector, spurs the discovery of new chemical entities. We review the approaches and technologies in use to identify anthelmintics and discuss a number of drug discovery paradigms that may prove pivotal to the next half-century of anthelmintic development.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Descoberta de Drogas
/
Helmintíase
/
Helmintos
/
Anti-Helmínticos
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article