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Microtubule-targeting agents augment the toxicity of DNA-damaging agents by disrupting intracellular trafficking of DNA repair proteins.
Poruchynsky, Marianne S; Komlodi-Pasztor, Edina; Trostel, Shana; Wilkerson, Julia; Regairaz, Marie; Pommier, Yves; Zhang, Xu; Kumar Maity, Tapan; Robey, Robert; Burotto, Mauricio; Sackett, Dan; Guha, Udayan; Fojo, Antonio Tito.
Afiliação
  • Poruchynsky MS; Center for Cancer Research.
  • Komlodi-Pasztor E; Center for Cancer Research.
  • Trostel S; Center for Cancer Research.
  • Wilkerson J; Center for Cancer Research.
  • Regairaz M; National Cancer Institute, Developmental Therapeutics Branch, National Cancer Institute, and.
  • Pommier Y; National Cancer Institute, Developmental Therapeutics Branch, National Cancer Institute, and.
  • Zhang X; Center for Cancer Research.
  • Kumar Maity T; Center for Cancer Research.
  • Robey R; National Cancer Institute, Developmental Therapeutics Branch, National Cancer Institute, and.
  • Burotto M; Center for Cancer Research.
  • Sackett D; Program in Physical Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.
  • Guha U; Center for Cancer Research.
  • Fojo AT; Center for Cancer Research, fojot@mail.nih.gov.
Proc Natl Acad Sci U S A ; 112(5): 1571-6, 2015 Feb 03.
Article em En | MEDLINE | ID: mdl-25605897
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / DNA / Reparo do DNA / Microtúbulos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / DNA / Reparo do DNA / Microtúbulos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article