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A phase 3 randomized, double-blind, placebo-controlled trial of ganitumab or placebo in combination with gemcitabine as first-line therapy for metastatic adenocarcinoma of the pancreas: the GAMMA trial.
Fuchs, C S; Azevedo, S; Okusaka, T; Van Laethem, J-L; Lipton, L R; Riess, H; Szczylik, C; Moore, M J; Peeters, M; Bodoky, G; Ikeda, M; Melichar, B; Nemecek, R; Ohkawa, S; Swieboda-Sadlej, A; Tjulandin, S A; Van Cutsem, E; Loberg, R; Haddad, V; Gansert, J L; Bach, B A; Carrato, A.
Afiliação
  • Fuchs CS; Department of Medical Oncology/Solid Tumor Oncology, Dana-Farber Cancer Institute, Boston, USA. Electronic address: charles_fuchs@dfci.harvard.edu.
  • Azevedo S; Oncology Service, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil.
  • Okusaka T; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan.
  • Van Laethem JL; Department of Gastroenterology, Erasme University Hospital, Brussels, Belgium.
  • Lipton LR; Medical Oncology, Royal Melbourne Hospital, Parkville, VIC, Australia.
  • Riess H; Department of Hematology, Oncology, and Tumor Immunology, Charité University, Berlin, Germany.
  • Szczylik C; Department of Oncology, Military Institute of Health Services, Warsaw, Poland.
  • Moore MJ; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
  • Peeters M; Department of Oncology, Antwerp University Hospital, Edegum, Belgium.
  • Bodoky G; Department of Oncology, St László Hospital, Budapest, Hungary.
  • Ikeda M; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
  • Melichar B; Department of Oncology, Palacký University Medical School and Teaching Hospital, Olomouc.
  • Nemecek R; Department of Oncology, Masaryk University Medical School and Masaryk Memorial Cancer Institute, Brno, Czech Republic.
  • Ohkawa S; Department of Gastroenterology, Kanagawa Cancer Center, Yokohama, Japan.
  • Swieboda-Sadlej A; Department of Haematology, Oncology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
  • Tjulandin SA; Department of Clinical Pharmacology and Chemotherapy, Russian Cancer Research Center, Moscow, Russia.
  • Van Cutsem E; Digestive Oncology, University Hospitals Gasthuisberg/Leuven and KU Leuven, Leuven, Belgium.
  • Loberg R; Medical Sciences, Amgen Inc., Thousand Oaks, USA.
  • Haddad V; Global Biostatistical Science, Amgen Ltd, Cambridge, UK.
  • Gansert JL; Global Development, Thousand Oaks.
  • Bach BA; Development Oncology Therapeutics, Amgen Inc., Thousand Oaks, USA.
  • Carrato A; Medical Oncology Department, University Hospital Ramon y Cajal, Madrid, Spain.
Ann Oncol ; 26(5): 921-927, 2015 May.
Article em En | MEDLINE | ID: mdl-25609246
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Adenocarcinoma / Protocolos de Quimioterapia Combinada Antineoplásica / Desoxicitidina / Anticorpos Monoclonais / Antimetabólitos Antineoplásicos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Adenocarcinoma / Protocolos de Quimioterapia Combinada Antineoplásica / Desoxicitidina / Anticorpos Monoclonais / Antimetabólitos Antineoplásicos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article