Supramolecular nanosubstrate-mediated delivery for reprogramming and transdifferentiation of mammalian cells.
Small
; 11(21): 2499-504, 2015 Jun 03.
Article
em En
| MEDLINE
| ID: mdl-25613059
ABSTRACT
Supramolecular nanosubstrate-mediated delivery (SNSMD) leverages the power of molecular self-assembly and a nanostructured substrate platform for the low toxicity, highly efficient co-delivery of biological factors encapsulated in a nanovector. Human fibroblasts are successfully reprogrammed into induced pluripotent stems and transdifferentiated into induced neuronal-like cells.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Reprogramação Celular
/
Transdiferenciação Celular
/
Técnicas de Reprogramação Celular
Limite:
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article