Chemical allergens stimulate human epidermal keratinocytes to produce lymphangiogenic vascular endothelial growth factor.

Bae, Ok-Nam; Ahn, Seyeon; Jin, Sun Hee; Hong, Soo Hyun; Lee, Jinyoung; Kim, Eun-Sun; Jeong, Tae Cheon; Chun, Young-Jin; Lee, Ai-Young; Noh, Minsoo

Bae, Ok-Nam; Ahn, Seyeon; Jin, Sun Hee; Hong, Soo Hyun; Lee, Jinyoung; Kim, Eun-Sun; Jeong, Tae Cheon; Chun, Young-Jin; Lee, Ai-Young; Noh, Minsoo.

Afiliação

Bae ON; College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 426-791, Republic of Korea.
Ahn S; College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 151-742, Republic of Korea.
Jin SH; College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 151-742, Republic of Korea.
Hong SH; College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 151-742, Republic of Korea.
Lee J; College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 151-742, Republic of Korea.
Kim ES; College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan 426-791, Republic of Korea.
Jeong TC; College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea.
Chun YJ; College of Pharmacy, Chung-Ang University, Seoul 156-756, Republic of Korea.
Lee AY; Department of Dermatology, Dongguk University Ilsan Hospital, Goyang 410-773, Republic of Korea. Electronic address: leeay@duih.org.
Noh M; College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 151-742, Republic of Korea. Electronic address: minsoo@alum.mit.edu.

Toxicol Appl Pharmacol ; 283(2): 147-55, 2015 Mar 01.

Article em En | MEDLINE | ID: mdl-25617811

Assuntos

Alérgenos/farmacologia; Epiderme/metabolismo; Queratinócitos/metabolismo; Linfangiogênese/fisiologia; Fator A de Crescimento do Endotélio Vascular/biossíntese; Animais; Sobrevivência Celular/efeitos dos fármacos; Sobrevivência Celular/fisiologia; Células Cultivadas; Relação Dose-Resposta a Droga; Epiderme/efeitos dos fármacos; Epiderme/imunologia; Prepúcio do Pênis/efeitos dos fármacos; Prepúcio do Pênis/imunologia; Prepúcio do Pênis/metabolismo; Humanos; Queratinócitos/efeitos dos fármacos; Queratinócitos/imunologia; Linfangiogênese/efeitos dos fármacos; Masculino; Camundongos

Palavras-chave

Allergic contact dermatitis (ACD); IL-8; Lymphangiogenesis; Normal human keratinocytes; OECD TG429; VEGF

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alérgenos / Queratinócitos / Fator A de Crescimento do Endotélio Vascular / Linfangiogênese / Epiderme Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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