Class I histone deacetylase-mediated repression of the proximal promoter of the activity-regulated cytoskeleton-associated protein gene regulates its response to brain-derived neurotrophic factor.

Fukuchi, Mamoru; Nakashima, Fukumi; Tabuchi, Akiko; Shimotori, Masataka; Tatsumi, Saori; Okuno, Hiroyuki; Bito, Haruhiko; Tsuda, Masaaki

Fukuchi, Mamoru; Nakashima, Fukumi; Tabuchi, Akiko; Shimotori, Masataka; Tatsumi, Saori; Okuno, Hiroyuki; Bito, Haruhiko; Tsuda, Masaaki.

Afiliação

Fukuchi M; From the Department of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan and.
Nakashima F; From the Department of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan and.
Tabuchi A; From the Department of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan and.
Shimotori M; From the Department of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan and.
Tatsumi S; From the Department of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan and.
Okuno H; the Department of Neurochemistry, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
Bito H; the Department of Neurochemistry, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
Tsuda M; From the Department of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan and tsuda@pha.u-toyama.ac.jp.

J Biol Chem ; 290(11): 6825-36, 2015 Mar 13.

Article em En | MEDLINE | ID: mdl-25623071

Assuntos

Fator Neurotrófico Derivado do Encéfalo/metabolismo; Proteínas do Citoesqueleto/genética; Histona Desacetilases/metabolismo; Proteínas do Tecido Nervoso/genética; Regiões Promotoras Genéticas; Ativação Transcricional; Animais; Sequência de Bases; Células Cultivadas; Proteína 1 de Resposta de Crescimento Precoce/metabolismo; Fator 2 de Crescimento de Fibroblastos/metabolismo; Dados de Sequência Molecular; Ratos; Ratos Sprague-Dawley; Receptores de N-Metil-D-Aspartato/metabolismo; Elementos de Resposta; Fator de Transcrição Sp4/metabolismo; Dedos de Zinco

Palavras-chave

activity-regulated cytoskeleton-associated protein; brain-derived neurotrophic factor (BDNF); histone deacetylase 1 (HDAC1); neuron; receptor tyrosine kinase; transcription regulation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ativação Transcricional / Regiões Promotoras Genéticas / Fator Neurotrófico Derivado do Encéfalo / Proteínas do Citoesqueleto / Histona Desacetilases / Proteínas do Tecido Nervoso Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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