Tunable nanostructured coating for the capture and selective release of viable circulating tumor cells.
Adv Mater
; 27(9): 1593-9, 2015 Mar 04.
Article
em En
| MEDLINE
| ID: mdl-25640006
ABSTRACT
A layer-by-layer gelatin nanocoating is presented for use as a tunable, dual response biomaterial for the capture and release of circulating tumor cells (CTCs) from cancer patient blood. The entire nanocoating can be dissolved from the surface of microfluidic devices through biologically compatible temperature shifts. Alternatively, individual CTCs can be released through locally applied mechanical stress.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Separação Celular
/
Técnicas Analíticas Microfluídicas
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Nanoestruturas
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Células Neoplásicas Circulantes
Tipo de estudo:
Evaluation_studies
Limite:
Humans
/
Male
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article