Protein-responsive assemblies from catechol-metal ion supramolecular coordination.
Soft Matter
; 11(11): 2243-50, 2015 Mar 21.
Article
em En
| MEDLINE
| ID: mdl-25648855
ABSTRACT
Supramolecular self-assembly driven by catechol-metal ion coordination has gained great success in the fabrication of functional materials including adhesives, capsules, coatings and hydrogels. However, this route has encountered a great challenge in the construction of nanoarchitectures in the absence of removable templates, because of the uncontrollable crosslinking of catechol-metal ion coordination. Herein, we show that a supramolecular approach, combining both catechol-metal ion coordination and polymer self-assembly together, can organize polymers into hybrid nanoassemblies ranging from solid particles, homogeneous vesicles to Janus vesicles. Without the introduction of a specific binding ligand or complicated molecular design, these assemblies can totally disassemble in response to proteins. UV/vis absorption, fluorescence quenching and recovery investigations have confirmed that proteins can seize metal ions from the hybrid nanoassemblies, thus causing the degradation of catechol-metal ion coordination networks.
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1
Base de dados:
MEDLINE
Assunto principal:
Soroalbumina Bovina
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Tripsina
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Catecóis
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Metais
Limite:
Animals
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article