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An acetyl-methyl switch drives a conformational change in p53.
Tong, Qiong; Mazur, Sharlyn J; Rincon-Arano, Hector; Rothbart, Scott B; Kuznetsov, Dmitry M; Cui, Gaofeng; Liu, Wallace H; Gete, Yantenew; Klein, Brianna J; Jenkins, Lisa; Mer, Georges; Kutateladze, Andrei G; Strahl, Brian D; Groudine, Mark; Appella, Ettore; Kutateladze, Tatiana G.
Afiliação
  • Tong Q; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
  • Mazur SJ; Laboratory of Cell Biology, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Rincon-Arano H; Basic Science Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Rothbart SB; Department of Biochemistry and Biophysics and the Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Kuznetsov DM; Department of Chemistry and Biochemistry, University of Denver, Denver, CO 80210, USA.
  • Cui G; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
  • Liu WH; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
  • Gete Y; Laboratory of Cell Biology, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Klein BJ; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
  • Jenkins L; Laboratory of Cell Biology, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Mer G; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
  • Kutateladze AG; Department of Chemistry and Biochemistry, University of Denver, Denver, CO 80210, USA.
  • Strahl BD; Department of Biochemistry and Biophysics and the Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  • Groudine M; Basic Science Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Radiation Oncology, University Washington School of Medicine, Seattle, WA 98109, USA.
  • Appella E; Laboratory of Cell Biology, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Kutateladze TG; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address: tatiana.kutateladze@ucdenver.edu.
Structure ; 23(2): 322-31, 2015 Feb 03.
Article em En | MEDLINE | ID: mdl-25651062
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Modelos Moleculares / Processamento de Proteína Pós-Traducional / Proteína Supressora de Tumor p53 / Metilação de DNA / Ligantes Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Modelos Moleculares / Processamento de Proteína Pós-Traducional / Proteína Supressora de Tumor p53 / Metilação de DNA / Ligantes Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article