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Design, synthesis, and biological evaluation of air-stable nafuredin-γ analogs as complex I inhibitors.
Ohtawa, Masaki; Matsunaga, Mari; Fukunaga, Keiko; Shimizu, Risa; Shimizu, Eri; Arima, Shiho; Ohmori, Junko; Kita, Kiyoshi; Shiomi, Kazuro; Omura, Satoshi; Nagamitsu, Tohru.
Afiliação
  • Ohtawa M; Graduate School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
  • Matsunaga M; Graduate School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
  • Fukunaga K; Graduate School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
  • Shimizu R; Graduate School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
  • Shimizu E; Graduate School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
  • Arima S; Graduate School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
  • Ohmori J; Department of Biomedical Chemistry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
  • Kita K; Department of Biomedical Chemistry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
  • Shiomi K; Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
  • Omura S; Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
  • Nagamitsu T; Graduate School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan. Electronic address: nagamitsut@pharm.kitasato-u.ac.jp.
Bioorg Med Chem ; 23(5): 932-43, 2015 Mar 01.
Article em En | MEDLINE | ID: mdl-25659618
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pironas / Desenho de Fármacos / Complexo I de Transporte de Elétrons / Inibidores Enzimáticos Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pironas / Desenho de Fármacos / Complexo I de Transporte de Elétrons / Inibidores Enzimáticos Idioma: En Ano de publicação: 2015 Tipo de documento: Article