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Dibenzosuberyl substituted polyamines and analogs of clomipramine as effective inhibitors of trypanothione reductase; molecular docking, and assessment of trypanocidal activities.
O'Sullivan, Mary C; Durham, Timothy B; Valdes, Hannah E; Dauer, Kelly L; Karney, Nicholas J; Forrestel, Andrew C; Bacchi, Cyrus J; Baker, Jerome F.
Afiliação
  • O'Sullivan MC; Department of Chemistry and Biochemistry, Canisius College, 2001 Main Street, Buffalo, NY 14208, USA. Electronic address: osulliv1@canisius.edu.
  • Durham TB; Department of Chemistry, Indiana State University, Terre Haute, IN 47809, USA.
  • Valdes HE; Department of Chemistry and Biochemistry, Canisius College, 2001 Main Street, Buffalo, NY 14208, USA.
  • Dauer KL; Department of Chemistry and Biochemistry, Canisius College, 2001 Main Street, Buffalo, NY 14208, USA.
  • Karney NJ; Department of Chemistry and Biochemistry, Canisius College, 2001 Main Street, Buffalo, NY 14208, USA.
  • Forrestel AC; Department of Chemistry and Biochemistry, Canisius College, 2001 Main Street, Buffalo, NY 14208, USA.
  • Bacchi CJ; Haskins Laboratories and Department of Biology, Pace University, New York, NY 10038, USA.
  • Baker JF; Department of Chemistry and Biochemistry, Canisius College, 2001 Main Street, Buffalo, NY 14208, USA.
Bioorg Med Chem ; 23(5): 996-1010, 2015 Mar 01.
Article em En | MEDLINE | ID: mdl-25661449
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poliaminas / Tripanossomicidas / Clomipramina / Inibidores Enzimáticos / NADH NADPH Oxirredutases Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poliaminas / Tripanossomicidas / Clomipramina / Inibidores Enzimáticos / NADH NADPH Oxirredutases Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article