Development of efficient chemical syntheses of vitamin D degradation products.
Anticancer Res
; 35(2): 1205-10, 2015 Feb.
Article
em En
| MEDLINE
| ID: mdl-25667512
ABSTRACT
In recent years it has been recognized that vitamin D deficiency is associated with a wide range of diseases, including various types of cancers. Due to the enormous medical importance of vitamin D and its metabolites, their status in blood serum has to be accurately measured. Thus, the metabolites actually used as reference standards and also others of relevant biological activity have to be provided for validation and continuous improvement of appropriate diagnostic devices. Efficient chemical syntheses of vitamin D derivatives described in the literature are herein proven in a comparative study and applied to the synthesis of some of the most relevant natural metabolites as representative examples.
Palavras-chave
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Vitamina D
Tipo de estudo:
Guideline
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article