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New genetic loci link adipose and insulin biology to body fat distribution.
Shungin, Dmitry; Winkler, Thomas W; Croteau-Chonka, Damien C; Ferreira, Teresa; Locke, Adam E; Mägi, Reedik; Strawbridge, Rona J; Pers, Tune H; Fischer, Krista; Justice, Anne E; Workalemahu, Tsegaselassie; Wu, Joseph M W; Buchkovich, Martin L; Heard-Costa, Nancy L; Roman, Tamara S; Drong, Alexander W; Song, Ci; Gustafsson, Stefan; Day, Felix R; Esko, Tonu; Fall, Tove; Kutalik, Zoltán; Luan, Jian'an; Randall, Joshua C; Scherag, André; Vedantam, Sailaja; Wood, Andrew R; Chen, Jin; Fehrmann, Rudolf; Karjalainen, Juha; Kahali, Bratati; Liu, Ching-Ti; Schmidt, Ellen M; Absher, Devin; Amin, Najaf; Anderson, Denise; Beekman, Marian; Bragg-Gresham, Jennifer L; Buyske, Steven; Demirkan, Ayse; Ehret, Georg B; Feitosa, Mary F; Goel, Anuj; Jackson, Anne U; Johnson, Toby; Kleber, Marcus E; Kristiansson, Kati; Mangino, Massimo; Leach, Irene Mateo; Medina-Gomez, Carolina.
Afiliação
  • Shungin D; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.
  • Winkler TW; Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.
  • Croteau-Chonka DC; Department of Odontology, Umeå University, Umeå 901 85, Sweden.
  • Ferreira T; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.
  • Locke AE; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Mägi R; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Strawbridge RJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
  • Pers TH; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Fischer K; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
  • Justice AE; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
  • Workalemahu T; Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.
  • Wu JMW; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.
  • Buchkovich ML; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02142, MA, USA.
  • Heard-Costa NL; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Roman TS; Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby 2800, Denmark.
  • Drong AW; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
  • Song C; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Gustafsson S; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.
  • Day FR; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.
  • Esko T; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Fall T; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham MA 01702, USA.
  • Kutalik Z; Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA.
  • Luan J; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Randall JC; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
  • Scherag A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.
  • Vedantam S; Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.
  • Wood AR; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.
  • Chen J; Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.
  • Fehrmann R; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.
  • Karjalainen J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
  • Kahali B; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
  • Liu CT; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.
  • Schmidt EM; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02142, MA, USA.
  • Absher D; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Amin N; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.
  • Anderson D; Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.
  • Beekman M; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.
  • Bragg-Gresham JL; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne 1010, Switzerland.
  • Buyske S; Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.
  • Demirkan A; Department of Medical Genetics, University of Lausanne, Lausanne 1005, Switzerland.
  • Ehret GB; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
  • Feitosa MF; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
  • Goel A; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
  • Jackson AU; Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany.
  • Johnson T; Clinical Epidemiology, Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany.
  • Kleber ME; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.
  • Kristiansson K; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02142, MA, USA.
  • Mangino M; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.
  • Leach IM; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.
  • Medina-Gomez C; Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Nature ; 518(7538): 187-196, 2015 Feb 12.
Article em En | MEDLINE | ID: mdl-25673412
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tecido Adiposo / Locos de Características Quantitativas / Distribuição da Gordura Corporal / Estudo de Associação Genômica Ampla / Insulina Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Female / Humans / Male País como assunto: Europa Idioma: En Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tecido Adiposo / Locos de Características Quantitativas / Distribuição da Gordura Corporal / Estudo de Associação Genômica Ampla / Insulina Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Female / Humans / Male País como assunto: Europa Idioma: En Ano de publicação: 2015 Tipo de documento: Article