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Inhibition of Pro-apoptotic BAX by a noncanonical interaction mechanism.
Barclay, Lauren A; Wales, Thomas E; Garner, Thomas P; Wachter, Franziska; Lee, Susan; Guerra, Rachel M; Stewart, Michelle L; Braun, Craig R; Bird, Gregory H; Gavathiotis, Evripidis; Engen, John R; Walensky, Loren D.
Afiliação
  • Barclay LA; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Wales TE; Department of Chemistry and Chemical Biology, Barnett Institute of Chemical and Biological Analysis, Northeastern University, Boston, MA 02115, USA.
  • Garner TP; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Wachter F; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Lee S; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Guerra RM; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Stewart ML; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Braun CR; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Bird GH; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Gavathiotis E; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Engen JR; Department of Chemistry and Chemical Biology, Barnett Institute of Chemical and Biological Analysis, Northeastern University, Boston, MA 02115, USA.
  • Walensky LD; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address: loren_walensky@dfci.harvard.edu.
Mol Cell ; 57(5): 873-886, 2015 Mar 05.
Article em En | MEDLINE | ID: mdl-25684204
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estrutura Terciária de Proteína / Estrutura Secundária de Proteína / Apoptose / Proteínas Proto-Oncogênicas c-bcl-2 / Proteína X Associada a bcl-2 Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estrutura Terciária de Proteína / Estrutura Secundária de Proteína / Apoptose / Proteínas Proto-Oncogênicas c-bcl-2 / Proteína X Associada a bcl-2 Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article