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BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair.
Hatchi, Elodie; Skourti-Stathaki, Konstantina; Ventz, Steffen; Pinello, Luca; Yen, Angela; Kamieniarz-Gdula, Kinga; Dimitrov, Stoil; Pathania, Shailja; McKinney, Kristine M; Eaton, Matthew L; Kellis, Manolis; Hill, Sarah J; Parmigiani, Giovanni; Proudfoot, Nicholas J; Livingston, David M.
Afiliação
  • Hatchi E; Department of Genetics, Harvard Medical School, Boston, MA 02215, USA; Department of Cancer Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA. Electronic address: elodiey_hatchi@dfci.harvard.edu.
  • Skourti-Stathaki K; Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.
  • Ventz S; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA; Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA.
  • Pinello L; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA; Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA.
  • Yen A; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Computer Science and Artificial Intelligence Laboratory (CSAIL), MIT, Cambridge, MA 02139, USA.
  • Kamieniarz-Gdula K; Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.
  • Dimitrov S; Department of Genetics, Harvard Medical School, Boston, MA 02215, USA; Department of Cancer Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.
  • Pathania S; Department of Genetics, Harvard Medical School, Boston, MA 02215, USA; Department of Cancer Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.
  • McKinney KM; Department of Genetics, Harvard Medical School, Boston, MA 02215, USA; Department of Cancer Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.
  • Eaton ML; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Computer Science and Artificial Intelligence Laboratory (CSAIL), MIT, Cambridge, MA 02139, USA.
  • Kellis M; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Computer Science and Artificial Intelligence Laboratory (CSAIL), MIT, Cambridge, MA 02139, USA.
  • Hill SJ; Department of Genetics, Harvard Medical School, Boston, MA 02215, USA; Department of Cancer Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.
  • Parmigiani G; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA; Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA.
  • Proudfoot NJ; Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK.
  • Livingston DM; Department of Genetics, Harvard Medical School, Boston, MA 02215, USA; Department of Cancer Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA. Electronic address: david_livingston@dfci.harvard.edu.
Mol Cell ; 57(4): 636-647, 2015 Feb 19.
Article em En | MEDLINE | ID: mdl-25699710
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína BRCA1 / RNA Helicases / Reparo do DNA / Modelos Genéticos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína BRCA1 / RNA Helicases / Reparo do DNA / Modelos Genéticos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article