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Design of high-throughput screening assays and identification of a SUMO1-specific small molecule chemotype targeting the SUMO-interacting motif-binding surface.
Alontaga, Aileen Y; Li, Yifei; Chen, Chih-Hong; Ma, Chen-Ting; Malany, Siobhan; Key, Danielle E; Sergienko, Eduard; Sun, Qing; Whipple, David A; Matharu, Daljit S; Li, Baozong; Vega, Ramir; Li, Yi-Jia; Schoenen, Frank J; Blagg, Brian S J; Chung, Thomas D Y; Chen, Yuan.
Afiliação
  • Alontaga AY; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States.
  • Li Y; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States.
  • Chen CH; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States.
  • Ma CT; ‡Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Institute, La Jolla, California 92037, United States.
  • Malany S; §Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Institute at Lake Nona, Orlando, Florida 32827, United States.
  • Key DE; §Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Institute at Lake Nona, Orlando, Florida 32827, United States.
  • Sergienko E; ‡Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Institute, La Jolla, California 92037, United States.
  • Sun Q; ‡Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Institute, La Jolla, California 92037, United States.
  • Whipple DA; ∥University of Kansas Specialized Chemistry Center, Lawrence, Kansas 66049, United States.
  • Matharu DS; ∥University of Kansas Specialized Chemistry Center, Lawrence, Kansas 66049, United States.
  • Li B; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States.
  • Vega R; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States.
  • Li YJ; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States.
  • Schoenen FJ; ∥University of Kansas Specialized Chemistry Center, Lawrence, Kansas 66049, United States.
  • Blagg BS; ∥University of Kansas Specialized Chemistry Center, Lawrence, Kansas 66049, United States.
  • Chung TD; ‡Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Institute, La Jolla, California 92037, United States.
  • Chen Y; †Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States.
ACS Comb Sci ; 17(4): 239-46, 2015 Apr 13.
Article em En | MEDLINE | ID: mdl-25719760
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Modificadoras Pequenas Relacionadas à Ubiquitina / Transferência Ressonante de Energia de Fluorescência Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Modificadoras Pequenas Relacionadas à Ubiquitina / Transferência Ressonante de Energia de Fluorescência Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article