Towards RIP using free-electron laser SFX data.
J Synchrotron Radiat
; 22(2): 249-55, 2015 Mar.
Article
em En
| MEDLINE
| ID: mdl-25723926
ABSTRACT
Here, it is shown that simulated native serial femtosecond crystallography (SFX) cathepsin B data can be phased by rapid ionization of sulfur atoms. Utilizing standard software adopted for radiation-damage-induced phasing (RIP), the effects on both substructure determination and phasing of the number of collected patterns and fluences are explored for experimental conditions already available at current free-electron laser facilities.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Conformação Proteica
/
Lesões por Radiação
/
Cristalografia por Raios X
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article