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Praeruptorin A inhibits in vitro migration of preosteoclasts and in vivo bone erosion, possibly due to its potential to target calmodulin.
Yeon, Jeong-Tae; Choi, Sik-Won; Ryu, Byung Jun; Kim, Kwang-Jin; Lee, Joo Yun; Byun, Byung Jin; Son, Young-Jin; Kim, Seong Hwan.
Afiliação
  • Yeon JT; †Research Institute of Basic Science and §Department of Pharmacy, Sunchon National University, Suncheon 540-742, Republic of Korea.
  • Choi SW; ‡Laboratory of Translational Therapeutics, Pharmacology Research Center, Drug Discovery Division, ⊥Korea Chemical Bank, and ∥Drug Discovery Platform Technology Group, Korea Research Institute of Chemical Technology, Daejeon 305-600, Republic of Korea.
  • Ryu BJ; †Research Institute of Basic Science and §Department of Pharmacy, Sunchon National University, Suncheon 540-742, Republic of Korea.
  • Kim KJ; ‡Laboratory of Translational Therapeutics, Pharmacology Research Center, Drug Discovery Division, ⊥Korea Chemical Bank, and ∥Drug Discovery Platform Technology Group, Korea Research Institute of Chemical Technology, Daejeon 305-600, Republic of Korea.
  • Lee JY; †Research Institute of Basic Science and §Department of Pharmacy, Sunchon National University, Suncheon 540-742, Republic of Korea.
  • Byun BJ; ‡Laboratory of Translational Therapeutics, Pharmacology Research Center, Drug Discovery Division, ⊥Korea Chemical Bank, and ∥Drug Discovery Platform Technology Group, Korea Research Institute of Chemical Technology, Daejeon 305-600, Republic of Korea.
  • Son YJ; †Research Institute of Basic Science and §Department of Pharmacy, Sunchon National University, Suncheon 540-742, Republic of Korea.
  • Kim SH; ‡Laboratory of Translational Therapeutics, Pharmacology Research Center, Drug Discovery Division, ⊥Korea Chemical Bank, and ∥Drug Discovery Platform Technology Group, Korea Research Institute of Chemical Technology, Daejeon 305-600, Republic of Korea.
J Nat Prod ; 78(4): 776-82, 2015 Apr 24.
Article em En | MEDLINE | ID: mdl-25734761
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoclastos / Calmodulina / Cumarínicos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoclastos / Calmodulina / Cumarínicos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article