Clinicoradiologic response of neurologic tuberculous mass lesions in children treated with thalidomide.
Pediatr Infect Dis J
; 34(2): 214-8, 2015 Feb.
Article
em En
| MEDLINE
| ID: mdl-25741973
ABSTRACT
Neurologic tuberculous pseudoabscesses that clinically progress despite conventional antituberculosis therapy may be responsive to adjuvant thalidomide, a potent tumor necrosis factor-α inhibitor. In this study, the addition of thalidomide provided substantial clinical benefit in the majority of patients, and magnetic resonance imaging evolution of lesions from early-stage "T2 bright" with edema to "T2 black" represented a marker of cure.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Talidomida
/
Tuberculose Meníngea
/
Imunossupressores
/
Antituberculosos
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Adolescent
/
Child
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Child, preschool
/
Female
/
Humans
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Infant
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Male
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article