[Successful treatment with azacitidine for myelodysplastic syndrome with large vessel vasculitis].
Rinsho Ketsueki
; 56(1): 35-7, 2015 Jan.
Article
em Ja
| MEDLINE
| ID: mdl-25745966
ABSTRACT
Paraneoplastic inflammation of the large vessels is a rare complication of myelodysplastic syndrome (MDS), and patients with MDS and systemic vasculitis have a poor prognosis. We present a 66-year-old male with MDS and large vessel vasculitis treated with azacitidine. Azacitidine administration improved his clinical symptoms, high fever and thickening of the arterial wall, and he achieved a complete bone marrow remission. However, 1 year later he showed progression of MDS. For MDS with vasculitis, intensive therapy, the same as that given to the high-risk group, should be considered and azacitidine administration may represent an efficacious treatment.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Azacitidina
/
Vasculite
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Síndromes Mielodisplásicas
/
Inibidores Enzimáticos
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Aged
/
Humans
/
Male
Idioma:
Ja
Ano de publicação:
2015
Tipo de documento:
Article