Steroidal sapogenins and glycosides from the fibrous roots of Ophiopogon japonicus and Liriope spicata var. prolifera with anti-inflammatory activity.
Chem Pharm Bull (Tokyo)
; 63(3): 187-94, 2015.
Article
em En
| MEDLINE
| ID: mdl-25757489
ABSTRACT
Two new steroidal glycosides (1 and 2), together with 15 known compounds (3-17) were isolated from the fibrous roots of Ophiopogon japonicus, and three new steroidal glycosides (18-20), together with 14 known compounds (21-34) were isolated from the fibrous roots of Liriope spicata var. prolifera. The structures of the new compounds were elucidated on the basis of extensive one-dimensional (1D)- and 2D-NMR spectroscopic analyses and mass spectrometry. The isolated compounds were evaluated for their anti-inflammatory activity in vitro. Most of these steroidal glycosides showed significant inhibitory activity against neutrophil respiratory burst stimulated by phorbol myristate acetate.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fitosteróis
/
Sapogeninas
/
Liriope (Planta)
/
Ophiopogon
/
Glicosídeos
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Anti-Inflamatórios
Limite:
Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article