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A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS.
Nagano, Seiichi; Takahashi, Yoko; Yamamoto, Kazuhiro; Masutani, Hiroshi; Fujiwara, Noriko; Urushitani, Makoto; Araki, Toshiyuki.
Afiliação
  • Nagano S; Department of Peripheral Nervous System Research.
  • Takahashi Y; Department of Peripheral Nervous System Research.
  • Yamamoto K; Division of Laboratory Animals Resources, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo 187-8502, Japan.
  • Masutani H; Department of Biological Responses, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan.
  • Fujiwara N; Department of Biochemistry, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan and.
  • Urushitani M; Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto 606-8705, Japan.
  • Araki T; Department of Peripheral Nervous System Research, taraki@ncnp.go.jp.
Hum Mol Genet ; 24(12): 3427-39, 2015 Jun 15.
Article em En | MEDLINE | ID: mdl-25762155
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Conformação Proteica / Superóxido Dismutase / Cisteína / Esclerose Lateral Amiotrófica / Neurônios Motores / Mutação Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Conformação Proteica / Superóxido Dismutase / Cisteína / Esclerose Lateral Amiotrófica / Neurônios Motores / Mutação Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article