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Translational arrest due to cytoplasmic redox stress delays adaptation to growth on methanol and heterologous protein expression in a typical fed-batch culture of Pichia pastoris.
Edwards-Jones, Bryn; Aw, Rochelle; Barton, Geraint R; Tredwell, Gregory D; Bundy, Jacob G; Leak, David J.
Afiliação
  • Edwards-Jones B; Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, London, SW7 2AZ, United Kingdom.
  • Aw R; Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, London, SW7 2AZ, United Kingdom.
  • Barton GR; Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, London, SW7 2AZ, United Kingdom.
  • Tredwell GD; Department of Surgery & Cancer, Faculty of Medicine, Imperial College London, London, SW7 2AZ, United Kingdom.
  • Bundy JG; Department of Surgery & Cancer, Faculty of Medicine, Imperial College London, London, SW7 2AZ, United Kingdom.
  • Leak DJ; Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, London, SW7 2AZ, United Kingdom; Department of Biology & Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom.
PLoS One ; 10(3): e0119637, 2015.
Article em En | MEDLINE | ID: mdl-25785713
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pichia / Biossíntese de Proteínas / Adaptação Fisiológica / Tripsina / Regulação Fúngica da Expressão Gênica / Metanol Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pichia / Biossíntese de Proteínas / Adaptação Fisiológica / Tripsina / Regulação Fúngica da Expressão Gênica / Metanol Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article