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Quantifying the impact of transporters on cellular drug permeability.
Matsson, Pär; Fenu, Luca A; Lundquist, Patrik; Wisniewski, Jacek R; Kansy, Manfred; Artursson, Per.
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  • Matsson P; Department of Pharmacy, Uppsala University, Box 580, SE-751 23 Uppsala, Sweden; Uppsala University Drug Optimization and Pharmaceutical Profiling Platform (UDOPP), Uppsala, Sweden; Science for Life Laboratory Drug Discovery and Development Platform, Uppsala University, Uppsala, Sweden. Electronic ad
  • Fenu LA; Department of Pharmacy, Uppsala University, Box 580, SE-751 23 Uppsala, Sweden; Uppsala University Drug Optimization and Pharmaceutical Profiling Platform (UDOPP), Uppsala, Sweden; Science for Life Laboratory Drug Discovery and Development Platform, Uppsala University, Uppsala, Sweden.
  • Lundquist P; Department of Pharmacy, Uppsala University, Box 580, SE-751 23 Uppsala, Sweden; Uppsala University Drug Optimization and Pharmaceutical Profiling Platform (UDOPP), Uppsala, Sweden; Science for Life Laboratory Drug Discovery and Development Platform, Uppsala University, Uppsala, Sweden.
  • Wisniewski JR; Biochemical Proteomics Group, Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Am Klopferspitz 18, D-82152 Martinsried, Germany.
  • Kansy M; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, 4070 Basel, Switzerland.
  • Artursson P; Department of Pharmacy, Uppsala University, Box 580, SE-751 23 Uppsala, Sweden; Uppsala University Drug Optimization and Pharmaceutical Profiling Platform (UDOPP), Uppsala, Sweden; Science for Life Laboratory Drug Discovery and Development Platform, Uppsala University, Uppsala, Sweden. Electronic ad
Trends Pharmacol Sci ; 36(5): 255-62, 2015 May.
Article em En | MEDLINE | ID: mdl-25799456
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Permeabilidade da Membrana Celular Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Permeabilidade da Membrana Celular Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article