In vivo cartilage strain increases following medial meniscal tear and correlates with synovial fluid matrix metalloproteinase activity.

Carter, Teralyn E; Taylor, Kevin A; Spritzer, Charles E; Utturkar, Gangadhar M; Taylor, Dean C; Moorman, Claude T; Garrett, William E; Guilak, Farshid; McNulty, Amy L; DeFrate, Louis E

Carter, Teralyn E; Taylor, Kevin A; Spritzer, Charles E; Utturkar, Gangadhar M; Taylor, Dean C; Moorman, Claude T; Garrett, William E; Guilak, Farshid; McNulty, Amy L; DeFrate, Louis E.

Afiliação

Carter TE; Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, United States.
Taylor KA; Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, United States.
Spritzer CE; Department of Radiology, Duke University Medical Center, Durham, NC, United States.
Utturkar GM; Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, United States.
Taylor DC; Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, United States.
Moorman CT; Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, United States.
Garrett WE; Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, United States.
Guilak F; Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, United States.
McNulty AL; Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, United States.
DeFrate LE; Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, United States.

J Biomech ; 48(8): 1461-8, 2015 Jun 01.

Article em En | MEDLINE | ID: mdl-25801424

Assuntos

Traumatismos do Joelho/fisiopatologia; Metaloproteinases da Matriz/metabolismo; Meniscos Tibiais/patologia; Líquido Sinovial/enzimologia; Fenômenos Biomecânicos; Proteína de Matriz Oligomérica de Cartilagem/metabolismo; Cartilagem Articular/enzimologia; Cartilagem Articular/fisiopatologia; Feminino; Humanos; Traumatismos do Joelho/enzimologia; Traumatismos do Joelho/cirurgia; Articulação do Joelho/fisiopatologia; Masculino; Meniscos Tibiais/enzimologia; Meniscos Tibiais/cirurgia; Pessoa de Meia-Idade; Amplitude de Movimento Articular

Palavras-chave

Aggrecan; Biomarker; COMP; Cartilage deformation; MRI; Mechanobiology

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Líquido Sinovial / Meniscos Tibiais / Metaloproteinases da Matriz / Traumatismos do Joelho Tipo de estudo: Risk_factors_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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