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Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators.
Jin, Shunying; Merchant, Michael L; Ritzenthaler, Jeffrey D; McLeish, Kenneth R; Lederer, Eleanor D; Torres-Gonzalez, Edilson; Fraig, Mostafa; Barati, Michelle T; Lentsch, Alex B; Roman, Jesse; Klein, Jon B; Rane, Madhavi J.
Afiliação
  • Jin S; Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America.
  • Merchant ML; Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America.
  • Ritzenthaler JD; Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America.
  • McLeish KR; Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America; Department of Biochemistry and Molecular Biology, University of Louisville, Louisville, Kentucky, United States of America; Robley Rex VA Medical Center, Zorn Avenue, Louisville, Kentucky, United States
  • Lederer ED; Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America; Robley Rex VA Medical Center, Zorn Avenue, Louisville, Kentucky, United States of America; Department of Physiology, University of Louisville, Louisville, Kentucky, United States of America.
  • Torres-Gonzalez E; Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America.
  • Fraig M; Department of Pathology, University of Louisville, Louisville, Kentucky, United States of America.
  • Barati MT; Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America.
  • Lentsch AB; Department of Surgery, University of Cincinnati, Cincinnati, OH, United States of America.
  • Roman J; Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America; Robley Rex VA Medical Center, Zorn Avenue, Louisville, Kentucky, United States of America.
  • Klein JB; Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America; Department of Biochemistry and Molecular Biology, University of Louisville, Louisville, Kentucky, United States of America; Robley Rex VA Medical Center, Zorn Avenue, Louisville, Kentucky, United States
  • Rane MJ; Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America; Department of Biochemistry and Molecular Biology, University of Louisville, Louisville, Kentucky, United States of America.
PLoS One ; 10(4): e0121637, 2015.
Article em En | MEDLINE | ID: mdl-25848767

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Baclofeno / Mediadores da Inflamação / Lesão Pulmonar Aguda / Agonistas dos Receptores de GABA-B / Complexo Antígeno-Anticorpo Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Baclofeno / Mediadores da Inflamação / Lesão Pulmonar Aguda / Agonistas dos Receptores de GABA-B / Complexo Antígeno-Anticorpo Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article