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Ni-Catalyzed C-H Functionalization in the Formation of a Complex Heterocycle: Synthesis of the Potent JAK2 Inhibitor BMS-911543.
Fitzgerald, Monica A; Soltani, Omid; Wei, Carolyn; Skliar, Dimitri; Zheng, Bin; Li, Jun; Albrecht, Jacob; Schmidt, Michael; Mahoney, Michelle; Fox, Richard J; Tran, Kristy; Zhu, Keming; Eastgate, Martin D.
Afiliação
  • Fitzgerald MA; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
  • Soltani O; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
  • Wei C; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
  • Skliar D; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
  • Zheng B; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
  • Li J; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
  • Albrecht J; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
  • Schmidt M; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
  • Mahoney M; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
  • Fox RJ; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
  • Tran K; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
  • Zhu K; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
  • Eastgate MD; Chemical Development, Bristol-Myers Squibb, One Squibb Drive, New Brunswick, New Jersey 08903, United States.
J Org Chem ; 80(12): 6001-11, 2015 Jun 19.
Article em En | MEDLINE | ID: mdl-25848821
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Janus Quinase 2 / Compostos Heterocíclicos com 3 Anéis / Níquel Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Janus Quinase 2 / Compostos Heterocíclicos com 3 Anéis / Níquel Idioma: En Ano de publicação: 2015 Tipo de documento: Article