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Vitreal delivery of AAV vectored Cnga3 restores cone function in CNGA3-/-/Nrl-/- mice, an all-cone model of CNGA3 achromatopsia.
Du, Wei; Tao, Ye; Deng, Wen-Tao; Zhu, Ping; Li, Jie; Dai, Xufeng; Zhang, Yuxin; Shi, Wei; Liu, Xuan; Chiodo, Vince A; Ding, Xi-Qin; Zhao, Chen; Michalakis, Stylianos; Biel, Martin; Zhang, Zuoming; Qu, Jia; Hauswirth, William W; Pang, Ji-Jing.
Afiliação
  • Du W; Deparment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA.
  • Tao Y; Deparment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA.
  • Deng WT; Deparment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA.
  • Zhu P; Deparment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA.
  • Li J; Deparment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA.
  • Dai X; Deparment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA, School of Ophthalmology and Optometry, The Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
  • Zhang Y; Deparment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA, Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University and State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China.
  • Shi W; Deparment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA.
  • Liu X; Deparment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA.
  • Chiodo VA; Deparment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA.
  • Ding XQ; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
  • Zhao C; Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University and State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China.
  • Michalakis S; Munich Center for Integrated Protein Science and Department of Pharmacy, Center for Drug Research, Ludwig-Maximilians-Universität München, 81377 Munich, Germany and.
  • Biel M; Munich Center for Integrated Protein Science and Department of Pharmacy, Center for Drug Research, Ludwig-Maximilians-Universität München, 81377 Munich, Germany and.
  • Zhang Z; Department of Clinical Aerospace Medicine, Fourth Military Medical University, Xi'an 710032, China jpang@ufl.edu.
  • Qu J; School of Ophthalmology and Optometry, The Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China, jpang@ufl.edu.
  • Hauswirth WW; Deparment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA, jpang@ufl.edu.
  • Pang JJ; Deparment of Ophthalmology, University of Florida, Gainesville, FL 32610, USA, School of Ophthalmology and Optometry, The Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China, Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University and State Key
Hum Mol Genet ; 24(13): 3699-707, 2015 Jul 01.
Article em En | MEDLINE | ID: mdl-25855802
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terapia Genética / Defeitos da Visão Cromática / Células Fotorreceptoras Retinianas Cones / Fatores de Transcrição de Zíper de Leucina Básica / Proteínas do Olho / Canais de Cátion Regulados por Nucleotídeos Cíclicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terapia Genética / Defeitos da Visão Cromática / Células Fotorreceptoras Retinianas Cones / Fatores de Transcrição de Zíper de Leucina Básica / Proteínas do Olho / Canais de Cátion Regulados por Nucleotídeos Cíclicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article