Quantification of in vivo ³¹P NMR brain spectra using LCModel.
NMR Biomed
; 28(6): 633-41, 2015 Jun.
Article
em En
| MEDLINE
| ID: mdl-25871439
ABSTRACT
Quantification of (31)P NMR spectra is commonly performed using line-fitting techniques with prior knowledge. Currently available time- and frequency-domain analysis software includes AMARES (in jMRUI) and CFIT respectively. Another popular frequency-domain approach is LCModel, which has been successfully used to fit both (1)H and (13)C in vivo NMR spectra. To the best of our knowledge LCModel has not been used to fit (31)P spectra. This study demonstrates the feasibility of using LCModel to quantify in vivo (31)P MR spectra, provided that adequate prior knowledge and LCModel control parameters are used. Both single-voxel and MRSI data are presented, and similar results are obtained with LCModel and with AMARES. This provides a new method for automated, operator-independent analysis of (31)P NMR spectra.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Isótopos de Fósforo
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Algoritmos
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Encéfalo
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Espectroscopia de Ressonância Magnética
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Compostos de Fósforo
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Modelos Biológicos
Tipo de estudo:
Diagnostic_studies
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Prognostic_studies
Limite:
Animals
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Humans
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article