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Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function in Primary Human Airway Epithelia.
Dong, Qian; Ernst, Sarah E; Ostedgaard, Lynda S; Shah, Viral S; Ver Heul, Amanda R; Welsh, Michael J; Randak, Christoph O.
Afiliação
  • Dong Q; From the Stead Family Department of Pediatrics.
  • Ernst SE; the Department of Internal Medicine, the Howard Hughes Medical Institute, Iowa City, Iowa 52242.
  • Ostedgaard LS; the Department of Internal Medicine.
  • Shah VS; the Department of Molecular Physiology and Biophysics, and the Medical Scientist Training Program, University of Iowa, Iowa City, Iowa 52242 and.
  • Ver Heul AR; From the Stead Family Department of Pediatrics.
  • Welsh MJ; the Department of Internal Medicine, the Howard Hughes Medical Institute, Iowa City, Iowa 52242 the Department of Molecular Physiology and Biophysics, and.
  • Randak CO; From the Stead Family Department of Pediatrics, christoph-randak@uiowa.edu.
J Biol Chem ; 290(22): 14140-53, 2015 May 29.
Article em En | MEDLINE | ID: mdl-25887396
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Brônquios / Adenilato Quinase / Transportadores de Cassetes de Ligação de ATP / Regulador de Condutância Transmembrana em Fibrose Cística / Glutamina Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Brônquios / Adenilato Quinase / Transportadores de Cassetes de Ligação de ATP / Regulador de Condutância Transmembrana em Fibrose Cística / Glutamina Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article