Overexpression of stathmin is resistant to paclitaxel treatment in patients with non-small cell lung cancer.

Sun, Ruifang; Liu, Zhigang; Wang, Lumin; Lv, Weidong; Liu, Jia; Ding, Caixia; Yuan, Yong; Lei, Guangyan; Xu, Changfu

Sun, Ruifang; Liu, Zhigang; Wang, Lumin; Lv, Weidong; Liu, Jia; Ding, Caixia; Yuan, Yong; Lei, Guangyan; Xu, Changfu.

Afiliação

Sun R; Department of Pathology, School of Medicine, Xi'an Jiaotong University, 76 Yanta West Road, Xi'an, 710061, Shaanxi, People's Republic of China. ruifang_sun@mail.xjtu.edu.cn.
Liu Z; Department of Thoracic Surgery, Tumor Hospital of Shaanxi Province, 309 Yanta West Road, Xi'an, Shaanxi, People's Republic of China.
Wang L; Key Laboratory of Environment and Genes Related to Diseases, School of Medicine, Xi'an Jiaotong University, 76 Yanta West Road, Xi'an, Shaanxi, People's Republic of China.
Lv W; Department of Thoracic Surgery, Tumor Hospital of Shaanxi Province, 309 Yanta West Road, Xi'an, Shaanxi, People's Republic of China.
Liu J; Department of Thoracic Surgery, Tumor Hospital of Shaanxi Province, 309 Yanta West Road, Xi'an, Shaanxi, People's Republic of China.
Ding C; Department of Pathology, Tumor Hospital of Shaanxi Province, 309 Yanta West Road, Xi'an, Shaanxi, People's Republic of China.
Yuan Y; Department of Pathology, Tumor Hospital of Shaanxi Province, 309 Yanta West Road, Xi'an, Shaanxi, People's Republic of China.
Lei G; Department of Thoracic Surgery, Tumor Hospital of Shaanxi Province, 309 Yanta West Road, Xi'an, Shaanxi, People's Republic of China.
Xu C; Department of Pathology, School of Medicine, Xi'an Jiaotong University, 76 Yanta West Road, Xi'an, 710061, Shaanxi, People's Republic of China.

Tumour Biol ; 36(9): 7195-204, 2015 Sep.

Article em En | MEDLINE | ID: mdl-25894372

Assuntos

Carcinoma Pulmonar de Células não Pequenas/genética; Paclitaxel/administração & dosagem; Estatmina/biossíntese; Tubulina (Proteína)/biossíntese; Adulto; Idoso; Idoso de 80 Anos ou mais; Protocolos de Quimioterapia Combinada Antineoplásica; Carcinoma Pulmonar de Células não Pequenas/tratamento farmacológico; Carcinoma Pulmonar de Células não Pequenas/patologia; Intervalo Livre de Doença; Resistencia a Medicamentos Antineoplásicos/genética; Feminino; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Humanos; Masculino; Pessoa de Meia-Idade; Prognóstico; Estatmina/genética; Tubulina (Proteína)/genética

Palavras-chave

Chemotherapy; NSCLC; Prognosis; STMN1; Sensitivity; TAX

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Paclitaxel / Carcinoma Pulmonar de Células não Pequenas / Estatmina Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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