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The lipid-lowering effects of lomitapide are unaffected by adjunctive apheresis in patients with homozygous familial hypercholesterolaemia - a post-hoc analysis of a Phase 3, single-arm, open-label trial.
Stefanutti, C; Blom, D J; Averna, M R; Meagher, E A; Theron, H dT; Marais, A D; Hegele, R A; Sirtori, C R; Shah, P K; Gaudet, D; Vigna, G B; Sachais, B S; Di Giacomo, S; du Plessis, A M E; Bloedon, L T; Balser, J; Rader, D J; Cuchel, M.
Afiliação
  • Stefanutti C; 'Sapienza' University of Rome, Rome, Italy.
  • Blom DJ; University of Cape Town, Cape Town, South Africa.
  • Averna MR; Università di Palermo, Palermo, Italy.
  • Meagher EA; University of Pennsylvania, Philadelphia, PA, USA.
  • Theron Hd; Netcare Private Hospital, Bloemfontein, South Africa.
  • Marais AD; University of Cape Town, Cape Town, South Africa.
  • Hegele RA; Robarts Research Institute and University of Western Ontario, London, ON, Canada.
  • Sirtori CR; Ospedale Niguarda, Milano, Italy.
  • Shah PK; Cedars-Sinai Heart Institute, Los Angeles, CA, USA.
  • Gaudet D; Université de Montreal, Chicoutimi, Canada.
  • Vigna GB; Università di Ferrara, Ferrara, Italy.
  • Sachais BS; University of Pennsylvania, Philadelphia, PA, USA.
  • Di Giacomo S; 'Sapienza' University of Rome, Rome, Italy.
  • du Plessis AM; University of Pretoria, South Africa.
  • Bloedon LT; Aegerion Pharmaceuticals, Cambridge, MA, USA.
  • Balser J; Veristat, Holliston, MA, USA.
  • Rader DJ; University of Pennsylvania, Philadelphia, PA, USA.
  • Cuchel M; University of Pennsylvania, Philadelphia, PA, USA. Electronic address: mcuchel@mail.med.upenn.edu.
Atherosclerosis ; 240(2): 408-14, 2015 Jun.
Article em En | MEDLINE | ID: mdl-25897792

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzimidazóis / Remoção de Componentes Sanguíneos / Homozigoto / Hiperlipoproteinemia Tipo II / LDL-Colesterol / Anticolesterolemiantes Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzimidazóis / Remoção de Componentes Sanguíneos / Homozigoto / Hiperlipoproteinemia Tipo II / LDL-Colesterol / Anticolesterolemiantes Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article