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Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acids.
Sodji, Quaovi H; Kornacki, James R; McDonald, John F; Mrksich, Milan; Oyelere, Adegboyega K.
Afiliação
  • Sodji QH; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332-0400, USA.
  • Kornacki JR; Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113, USA; Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113, USA.
  • McDonald JF; School of Biology, Georgia Institute of Technology, Atlanta, GA 30332-0400, USA; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332-0400, USA.
  • Mrksich M; Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113, USA; Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113, USA. Electronic address: milan.mrksich@northwestern.edu.
  • Oyelere AK; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332-0400, USA; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332-0400, USA. Electronic address: aoyelere@gatech.edu.
Eur J Med Chem ; 96: 340-59, 2015.
Article em En | MEDLINE | ID: mdl-25899338
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pterinas / Desenho de Fármacos / Histona Desacetilase 1 / Inibidores de Histona Desacetilases / Ácido Fólico / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pterinas / Desenho de Fármacos / Histona Desacetilase 1 / Inibidores de Histona Desacetilases / Ácido Fólico / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article